Slay the Spire 2 Guide

About

Your one-stop shop for Slay the Spire 2 information. Explore a database of 567 cards and 286 relics, along with class strategies and ranked item lists. Also features a co-op synergy tool. Ready for Early Access 2026. Make informed decisions with the Damage Calculator, which allows you to simulate card interactions with Strength, Vulnerable, Block, and Poison to determine lethal potential. The Co-op Synergy Builder helps you select the optimal team composition from 2 to 4 players by highlighting synergistic cards and class combinations, and showing how scaling improves with more players.